We examined the published relationship between uterine fibroids and reproductive
outcomes. Submucosal fibroids had the strongest association with lower ongoing pregnancy
rates, odds ratio, 0.5; 95% confidence interval, 0.3-0.8, primarily through decreased
implantation. Cumulative pregnancy rates appeared slightly lower in patients with intramural
fibroids 36.9% vs 41.1%, which may reflect biases in the literature; however, patients with
intramural fibroids also experienced more miscarriages, 20.4% vs 12.9%. Adverse obstetric …