Results: The foetal haemoglobin level of 69 sickle cell disease patients (subjects) and 30
apparently healthy individual with genotype AA (control) was determined. The mean HbF
and packed cell volume was significantly higher among the 69 sickle cell disease subjects
(2.99±5.16) compared to controls (0.733±0.700)(p= 0.01). The packed cell volume was
significantly higher among control participants (29.267±6.175) compared to the sickle cell
disease subjects (24.57±6.99). Haemoglobin F level was compared based on the gender of …

Background: Sickle-cell disease (SCD) is a global public health problem occurring more
commonly among people in the tropical and sub-tropical sub-Saharan regions where
malaria is endemic. In this present study, we have investigated the haemoglobin F level
(HBF) of 69 sickle cell disease subjects and 30 age and gender-matched apparently healthy
controls. Methods: This case–control study was conducted among homozygous sickle cell
patients attending the sickle cell clinics of Specialist Hospital Sokoto. About 3 milliliters of …