BACKGROUND: Local management for vestibular schwannoma (VS) is associated with
excellent local control with focus on preserving long-term serviceable hearing. Fractionated
proton radiation therapy (FPRT) may be associated with greater hearing preservation
because of unique dosimetric properties of proton radiotherapy. OBJECTIVE: To investigate
hearing preservation rates of FPRT in adults with VS and secondarily assess local control
and treatment-related toxicity. METHODS: A prospective, single-arm, phase 2 clinical trial …

Purpose/Objective (s) Management for vestibular schwannoma (VS) achieves excellent
local control, and advances have increasingly focused on long-term serviceable hearing
preservation. Fractionated stereotactic radiation therapy (FSRT) is associated with better
hearing preservation compared to stereotactic radiosurgery (SRS). Fractionated proton
beam radiation therapy (FPRT) may be associated with greater hearing preservation due to
unique dosimetric properties of proton radiotherapy. Materials/Methods A single institution …