From biomass to medicines. A simple synthesis of indolo [3, 2-c] quinolines, antimalarial alkaloid isocryptolepine, and its derivatives
MG Uchuskin, AS Pilipenko, OV Serdyuk… - Organic & …, 2012 - pubs.rsc.org
MG Uchuskin, AS Pilipenko, OV Serdyuk, IV Trushkov, AV Butin
Organic & Biomolecular Chemistry, 2012•pubs.rsc.orgIndolo [3, 2-c] quinolines are pharmacologically attractive class of heterocyclic compounds.
The method of their synthesis, based on transformation of furfural, which is a large-scale
product of treatment of biomass including agricultural and forestry wastes, has been
developed. This method was utilized for the total synthesis of antimalarial alkaloid
isocryptolepine and its derivatives.
The method of their synthesis, based on transformation of furfural, which is a large-scale
product of treatment of biomass including agricultural and forestry wastes, has been
developed. This method was utilized for the total synthesis of antimalarial alkaloid
isocryptolepine and its derivatives.
Indolo[3,2-c]quinolines are pharmacologically attractive class of heterocyclic compounds. The method of their synthesis, based on transformation of furfural, which is a large-scale product of treatment of biomass including agricultural and forestry wastes, has been developed. This method was utilized for the total synthesis of antimalarial alkaloid isocryptolepine and its derivatives.
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