Functional antioxidant responsive elements

WW Wasserman, WE Fahl - Proceedings of the National …, 1997 - National Acad Sciences
… The transcriptional activation of the chemoprotective response genes by these … called the
antioxidant responsive element (ARE) (14), or, alternatively, the electrophile response element (…

Antioxidant response element

AK Jaiswal - Biochemical pharmacology, 1994 - Elsevier
… This is in contrast to the reports on rat GST-P gene and mouse GST-Ya subunit gene
ARES, which require the presence of both of the APl-like elements for their proper function [8,23]. …

The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity

TH Rushmore, MR Morton, CB Pickett - Journal of Biological Chemistry, 1991 - Elsevier
… , we examined the contribution of each responsive element to the transcriptional activation
of … This sequence, which has been named the electrophile responsive element, contains the …

[HTML][HTML] Antioxidant response elements: Discovery, classes, regulation and potential applications

A Raghunath, K Sundarraj, R Nagarajan, F Arfuso… - Redox biology, 2018 - Elsevier
… it possible to study the regulatory elements of phase II genes. … regulatory element called
antioxidant response element (ARE). … The element responsive to β-NF is found to be functional

Molecular basis for the contribution of the antioxidant responsive element to cancer chemoprevention

JD Hayes, M McMahon - Cancer letters, 2001 - Elsevier
… the antioxidant responsive element (ARE), whilst bifunctional inducers act through the ARE
as well as the xenobiotic responsive element (… Functional antioxidant responsive elements

Identification of a functional antioxidant response element within the eighth intron of the human ABCC3 gene

MJ Canet, MD Merrell, BG Harder, JM Maher… - Drug Metabolism and …, 2015 - ASPET
… one of these putative AREs is functionally active. Finally, DNA pull-… Our findings identify a
functional Nrf2 response element … the induction of ABCC3 during antioxidant response stimuli. …

Regulatory mechanisms controlling gene expression mediated by the antioxidant response element

T Nguyen, PJ Sherratt, CB Pickett - Annual review of …, 2003 - annualreviews.org
… Rushmore TH, Morton MR, Pickett CB, 1991; The antioxidant responsive element. Activation
by oxidative stress and identification of the DNAconsensus sequence required for functional

Identification of polymorphic antioxidant response elements in the human genome

X Wang, DJ Tomso, BN Chorley, HY Cho… - Human molecular …, 2007 - academic.oup.com
… We developed an integrated computational system for discovering functional SNPs in …
been tested to identify functional polymorphisms in the antioxidant response element (ARE), …

Carotenoids activate the antioxidant response element transcription system

A Ben-Dor, M Steiner, L Gheber, M Danilenko… - Molecular Cancer …, 2005 - AACR
… Expression of phase II enzymes is regulated by the antioxidant response element (ARE)
and the … This further supports our hypothesis that the functional Nrf2 protein and the ARE …

Integrating iron and oxygen/antioxidant signals via a combinatorial array of DNA–(antioxidant response elements) and mRNA (iron responsive elements) sequences

EC Theil - Journal of inorganic biochemistry, 2006 - Elsevier
… ) and mRNA (IRE-iron responsive element) structures. More is … Iron responsive elements
are very similar (65–80% … The potential of manipulating mRNA function with small molecules …