Functional network analysis identifies multiple virulence and antibiotic resistance targets in Stenotrophomonas maltophilia

L Pinto, RP Shastry, S Alva, RSP Rao, SD Ghate - Microbial Pathogenesis, 2023 - Elsevier
Stenotrophomonas maltophilia, an emerging multidrug-resistant opportunistic bacterium in
humans is of major concern for immunocompromised individuals for causing pneumonia
and bloodborne infections. This bacterial pathogen is associated with a considerable
fatality/case ratio, with up to 100%, when presented as hemorrhagic fever. It is resistant to
commonly used drugs as well as to antibiotic combinations. In-silico based functional
network analysis is a key approach to get novel insights into virulence and resistance in …
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