[HTML][HTML] Gamma aminobutyric acidergic and neuronal structural markers in the nucleus accumbens core underlie trait-like impulsive behavior

D Caprioli, SJ Sawiak, E Merlo, DEH Theobald… - Biological …, 2014 - Elsevier
Background Pathological forms of impulsivity are manifest in a number of psychiatric
disorders listed in DSM-5, including attention-deficit/hyperactivity disorder and substance
use disorder. However, the molecular and cellular substrates of impulsivity are poorly
understood. Here, we investigated a specific form of motor impulsivity in rats, namely
premature responding, on a five-choice serial reaction time task. Methods We used in vivo
voxel-based magnetic resonance imaging and ex vivo Western blot analyses to investigate …
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