[HTML][HTML] Genome-wide analysis reveals selection for important traits in domestic horse breeds
Intense selective pressures applied over short evolutionary time have resulted in
homogeneity within, but substantial variation among, horse breeds. Utilizing this population
structure, 744 individuals from 33 breeds, and a 54,000 SNP genotyping array, breed-
specific targets of selection were identified using an FST-based statistic calculated in 500-kb
windows across the genome. A 5.5-Mb region of ECA18, in which the myostatin (MSTN)
gene was centered, contained the highest signature of selection in both the Paint and …
homogeneity within, but substantial variation among, horse breeds. Utilizing this population
structure, 744 individuals from 33 breeds, and a 54,000 SNP genotyping array, breed-
specific targets of selection were identified using an FST-based statistic calculated in 500-kb
windows across the genome. A 5.5-Mb region of ECA18, in which the myostatin (MSTN)
gene was centered, contained the highest signature of selection in both the Paint and …
Genome-wide analysis reveals selection for important traits in domestic horse breeds
JR Mickelson, AK Rendahl, SJ Valberg… - Plos Genetics 1 (9 …, 2013 - agris.fao.org
Intense selective pressures applied over short evolutionary time have resulted in
homogeneity within, but substantial variation among, horse breeds. Utilizing this population
structure, 744 individuals from 33 breeds, and a 54,000 SNP genotyping array, breed-
specific targets of selection were identified using an F (ST)-based statistic calculated in 500-
kb windows across the genome. A 5.5-Mb region of ECA18, in which the myostatin (MSTN)
gene was centered, contained the highest signature of selection in both the Paint and …
homogeneity within, but substantial variation among, horse breeds. Utilizing this population
structure, 744 individuals from 33 breeds, and a 54,000 SNP genotyping array, breed-
specific targets of selection were identified using an F (ST)-based statistic calculated in 500-
kb windows across the genome. A 5.5-Mb region of ECA18, in which the myostatin (MSTN)
gene was centered, contained the highest signature of selection in both the Paint and …
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