Background Active pulmonary tuberculosis is difficult to diagnose and treatment response is
difficult to effectively monitor. A WHO consensus statement has called for new non-sputum
diagnostics. The aim of this study was to use an integrated multicohort analysis of samples
from publically available datasets to derive a diagnostic gene set in the peripheral blood of
patients with active tuberculosis. Methods We searched two public gene expression
microarray repositories and retained datasets that examined clinical cohorts of active …