Gut microbial and short-chain fatty acid profiles in adults with chronic constipation before and after treatment with lubiprostone
Identifying specific gut microorganisms associated with chronic constipation may be useful
for diagnostic and therapeutic purposes. The objective of this study was to evaluate whether
or not the gut microbial community of constipated subjects had specific microbial signatures
and to assess the effects of lubiprostone treatment on the gut microbial community. Stool
diaries, breath H 2 and CH 4 levels, and stool samples were collected from ten healthy
subjects and nine patients meeting the Rome III criteria for chronic functional constipation …
for diagnostic and therapeutic purposes. The objective of this study was to evaluate whether
or not the gut microbial community of constipated subjects had specific microbial signatures
and to assess the effects of lubiprostone treatment on the gut microbial community. Stool
diaries, breath H 2 and CH 4 levels, and stool samples were collected from ten healthy
subjects and nine patients meeting the Rome III criteria for chronic functional constipation …
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