Healing of large periapical lesions following delivery of dental stem cells with an injectable scaffold: new method and three case reports

V Shiehzadeh, F Aghmasheh… - Indian Journal of …, 2014 - journals.lww.com
Regenerative endodontics is the creation and delivery of tissues to replace diseased,
missing, and traumatized pulp. A call for a paradigm shift and new protocol for the clinical
management of these cases has been brought to attention. These regenerative endodontic
techniques will possibly involve some combination of disinfection or debridement of infected
root canal systems with apical enlargement to permit revascularization and use of stem cells,
scaffolds, and growth factors. Mesenchymal stem cells (MSCs) have been isolated from the …
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