Hematopoietic-specific microRNA expression in human cells

SH Ramkissoon, LA Mainwaring, Y Ogasawara… - Leukemia research, 2006 - Elsevier
We examined expression profiles of hematopoietic tissue-specific microRNAs (miRNAs; miR-
142, miR-155, miR-181 and miR-223) in 17 commercially available malignant hematopoietic
cell lines and compared to those in highly purified normal human B, T, monocytic and
granulocytic lineages. Although malignant cell lines examined showed miRNA expression
patterns similar to normal human hematopoietic lineages, the levels of miRNA expression
among cell lines and normal cell lineages were considerably different, indicating the …
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