Hidden genomic features of an invasive malaria vector, Anopheles stephensi, revealed by a chromosome-level genome assembly
Abstract Background The mosquito Anopheles stephensi is a vector of urban malaria in Asia
that recently invaded Africa. Studying the genetic basis of vectorial capacity and engineering
genetic interventions are both impeded by limitations of a vector's genome assembly. The
existing assemblies of An. stephensi are draft-quality and contain thousands of sequence
gaps, potentially missing genetic elements important for its biology and evolution. Results To
access previously intractable genomic regions, we generated a reference-grade genome …
that recently invaded Africa. Studying the genetic basis of vectorial capacity and engineering
genetic interventions are both impeded by limitations of a vector's genome assembly. The
existing assemblies of An. stephensi are draft-quality and contain thousands of sequence
gaps, potentially missing genetic elements important for its biology and evolution. Results To
access previously intractable genomic regions, we generated a reference-grade genome …
Hidden genomic features of an invasive malaria vector, Anopheles stephensi
Abstract Background The mosquito Anopheles stephensi is a vector of urban malaria in Asia
that recently invaded Africa. Studying the genetic basis of vectorial capacity and engineering
genetic interventions are both impeded by limitations of a vector's genome assembly. The
existing assemblies of An. stephensi are draft-quality and contain thousands of sequence
gaps, potentially missing genetic elements important for its biology and evolution. Results To
access previously intractable genomic regions, we generated a reference-grade genome …
that recently invaded Africa. Studying the genetic basis of vectorial capacity and engineering
genetic interventions are both impeded by limitations of a vector's genome assembly. The
existing assemblies of An. stephensi are draft-quality and contain thousands of sequence
gaps, potentially missing genetic elements important for its biology and evolution. Results To
access previously intractable genomic regions, we generated a reference-grade genome …
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