High-dose dexamethasone and oxygen support strategies in intensive care unit patients with severe COVID-19 acute hypoxemic respiratory failure: the COVIDICUS …
Importance The benefit of high-dose dexamethasone and oxygenation strategies vs
standard of care for patients with severe acute hypoxemic respiratory failure (AHRF) caused
by COVID-19 pneumonia is debated. Objectives To assess the benefit of high-dose
dexamethasone compared with standard of care dexamethasone, and to assess the benefit
of high-flow nasal oxygen (HFNo 2) or continuous positive airway pressure (CPAP)
compared with oxygen support standard of care (o 2 SC). Design, Setting, and Participants …
standard of care for patients with severe acute hypoxemic respiratory failure (AHRF) caused
by COVID-19 pneumonia is debated. Objectives To assess the benefit of high-dose
dexamethasone compared with standard of care dexamethasone, and to assess the benefit
of high-flow nasal oxygen (HFNo 2) or continuous positive airway pressure (CPAP)
compared with oxygen support standard of care (o 2 SC). Design, Setting, and Participants …
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