Cancer is a disease with high prevalence in western and industrialized countries. The
incidence of cancer has been increasing, while mortality has either been stable or
decreasing over the last years [1]. Clinical classification of tumors is complex and
inadequate, as similar tumors often experience different clinical outcomes. A need exists for
better clinically useful prognostic factors to identify cancer patients at minimal risk of relapse,
patients with a more serious prognosis, or patients who are likely to benefit from specific …