… micrometer-sized spots of nucleic acid with high resolution). … label on an acetyl phosphate
substrate is measured using the … This challenges even the most sensitive analytical methods. …

… most sensitive assays require a secondary detection technology, eg a label, since a nucleic
acid … Signal amplication system for DNA hybridization assays based on in vitro expression of …

… first nucleic acid hybridization studies used … site on the 5' end was hybridized to the target
fragments. When it is bound to the target site, the probe possessing the HincII recognition site (…

… for in vitro selections is their acceptance as a substrate by the nucleic acid replicating …
have made possible mutational studies, focussed at selected conserved sites, with the aim …

… Some of these invitro–evolved nucleic acid enzymes have a … highly sensitive so that even
if the desiredmolecules are very … ribonucleotide that defines the cleavage site, suchambiguity …

… All SELEX studies can be generally divided into two groups. … preferences for the isolation
of affine aptamers [36]. Such … required a very complex scheme to add primer-binding sites. …

… Special attention will be paid to NATs with high sensitivity, … are also highly required for
achieving on-site clinical tests or … strategy for specific nucleic acid replication in vitro through an …

… may be necessary for in vitro diagnostic assays. Unlike proteins, … in which the single
ribonucleotide at the cleavage site is … work at physiologically-relevant settings, we need to …

… Nucleic acid aptamers are logical choices for probe … method, however, this review centers
on fluorescence detection, … immobilized oligonucleotides with in vitro cloning techniques as …

… hybridise to the target (at adjacent sites) and another, much shorter… Breakdown of the alkaline
phosphatase substrate is measured, by … ) NASBA isothermal enzymatic in vitro nucleic acid …