Hippocampus and basal ganglia as potential sentinel sites for ischemic pathology after resuscitated cardiac arrest
M Haglund, E Lindberg, E Englund - Resuscitation, 2019 - Elsevier
Aims of the study Neurological impairment after resuscitated cardiac arrest (CA) remains a
significant unmet medical need. Brain ischemia associated with CA and subsequent
reperfusion is evident as two fundamentally different types of damage on neuropathological
examination: frank necrosis (involving all cell types) and selective eosinophilic neuronal
death (SEND). These types of damage are not only dissimilar in micromorphology, but also
differently detectable with clinical brain imaging methods. In a previous study, SEND was …
significant unmet medical need. Brain ischemia associated with CA and subsequent
reperfusion is evident as two fundamentally different types of damage on neuropathological
examination: frank necrosis (involving all cell types) and selective eosinophilic neuronal
death (SEND). These types of damage are not only dissimilar in micromorphology, but also
differently detectable with clinical brain imaging methods. In a previous study, SEND was …
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