How does fat survive and remodel after grafting?

T Mashiko, K Yoshimura - Clinics in plastic surgery, 2015 - plasticsurgery.theclinics.com
Adipose tissue and adipose-derived stem/stromal cells (ASCs) obtained from liposuction
were shown to have potential for regenerative therapeutic use. However, clinical outcomes
of fat grafting remain unpredictable and, to improve the outcomes, it is crucial to elucidate
the detailed mechanism of engraftment of fat tissue. The “cell survival theory,” which
maintains that transplanted adipocytes partly survive once they receive adequate nutrients
and remain alive in the recipient site, had been accepted for a long time. 1–3 In contrast, our …
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