Background: Human TP53 is the gatekeeper for generation of human cells and is highly
conserved. Any alteration/mutation to TP53 adversely affects the regulatory function of the
protein, potentially resulting in cancer. This study investigated mutations in codons 7 and
249 of TP53, among patients with hepatocellular carcinoma (HCC) and chronic hepatitis B
virus (HBV) infection at the Moi Teaching and Referral Hospital (MTRH), Eldoret, Kenya.
Methods: In total, 33 HBV-positive patients attending MTRH hospital between September …

Background Human TP53 is the gatekeeper for generation of human cells and is highly
conserved. Some alteration/mutation in TP53 adversely affects the regulatory function of the
protein, potentially resulting in cancer. This study investigated mutations in codons 72 and
249 of TP53, among patients with hepatocellular carcinoma (HCC) and chronic hepatitis B
virus (HBV) infection at the Moi Teaching and Referral Hospital (MTRH), Eldoret, Kenya.
Methods In total, 33 HBV-positive patients attending MTRH hospital between September …