Hyaluronan mixed esters of butyric and retinoic acid drive cardiac and endothelial fate in term placenta human mesenchymal stem cells and enhance cardiac repair in …
We have developed a mixed ester of hyaluronan with butyric and retinoic acid (HBR) that
acted as a novel cardiogenic/vasculogenic agent in human mesenchymal stem cells
isolated from bone marrow, dental pulp, and fetal membranes of term placenta (FMhMSCs).
HBR remarkably enhanced vascular endothelial growth factor (VEGF), KDR, and hepatocyte
growth factor (HGF) gene expression and the secretion of the angiogenic, mitogenic, and
antiapoptotic factors VEGF and HGF, priming stem cell differentiation into endothelial cells …
acted as a novel cardiogenic/vasculogenic agent in human mesenchymal stem cells
isolated from bone marrow, dental pulp, and fetal membranes of term placenta (FMhMSCs).
HBR remarkably enhanced vascular endothelial growth factor (VEGF), KDR, and hepatocyte
growth factor (HGF) gene expression and the secretion of the angiogenic, mitogenic, and
antiapoptotic factors VEGF and HGF, priming stem cell differentiation into endothelial cells …
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