Ibogan, Tacaman, and Cytotoxic Bisindole Alkaloids from Tabernaemontana. Cononusine, an Iboga Alkaloid with Unusual Incorporation of a Pyrrolidone Moiety
Six new indole alkaloids, viz., cononusine (1, a rare example of an iboga–pyrrolidone
conjugate), ervaluteine (2), vincamajicine (3), tacamonidine (4), 6-oxoibogaine (5), and N 4-
chloromethylnorfluorocurarine chloride (6), and two new vobasinyl-iboga bisindole
alkaloids, ervatensines A (7) and B (8), in addition to other known alkaloids, were isolated
from the stem-bark extract of the Malayan Tabernaemontana corymbosa. The structures of
these alkaloids were established on the basis of NMR and MS analyses and, in one …
conjugate), ervaluteine (2), vincamajicine (3), tacamonidine (4), 6-oxoibogaine (5), and N 4-
chloromethylnorfluorocurarine chloride (6), and two new vobasinyl-iboga bisindole
alkaloids, ervatensines A (7) and B (8), in addition to other known alkaloids, were isolated
from the stem-bark extract of the Malayan Tabernaemontana corymbosa. The structures of
these alkaloids were established on the basis of NMR and MS analyses and, in one …
Ibogan, tacaman, and cytotoxic bisindole alkaloids from Tabernaemontana. Cononusine, an iboga alkaloid with unusual incorporation of a pyrrolidone moiety.
LKH Lim KuanHon, VJ Raja, TD Bradshaw… - 2015 - cabidigitallibrary.org
Six new indole alkaloids, viz., cononusine (1, a rare example of an iboga-pyrrolidone
conjugate), ervaluteine (2), vincamajicine (3), tacamonidine (4), 6-oxoibogaine (5), and N 4-
chloromethylnorfluorocurarine chloride (6), and two new vobasinyl-iboga bisindole
alkaloids, ervatensines A (7) and B (8), in addition to other known alkaloids, were isolated
from the stem-bark extract of the Malayan Tabernaemontana corymbosa. The structures of
these alkaloids were established on the basis of NMR and MS analyses and, in one …
conjugate), ervaluteine (2), vincamajicine (3), tacamonidine (4), 6-oxoibogaine (5), and N 4-
chloromethylnorfluorocurarine chloride (6), and two new vobasinyl-iboga bisindole
alkaloids, ervatensines A (7) and B (8), in addition to other known alkaloids, were isolated
from the stem-bark extract of the Malayan Tabernaemontana corymbosa. The structures of
these alkaloids were established on the basis of NMR and MS analyses and, in one …
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