Identification of pro-and mature brain-derived neurotrophic factor in human saliva
AL Mandel, H Ozdener, V Utermohlen - Archives of oral biology, 2009 - Elsevier
OBJECTIVE: Growth factors, including brain-derived neurotrophic factor (BDNF), are
polypeptides that are involved in the maintenance, survival, and death of central and
peripheral cells. Numerous growth factors have been identified in saliva and are thought to
promote wound healing and maintenance of the oral epithelium. The aim of this study was to
determine if BDNF is also found in human saliva. METHODS: Whole, unstimulated saliva
samples (n= 30) were analyzed by SDS-PAGE and Western blot using an anti-human BDNF …
polypeptides that are involved in the maintenance, survival, and death of central and
peripheral cells. Numerous growth factors have been identified in saliva and are thought to
promote wound healing and maintenance of the oral epithelium. The aim of this study was to
determine if BDNF is also found in human saliva. METHODS: Whole, unstimulated saliva
samples (n= 30) were analyzed by SDS-PAGE and Western blot using an anti-human BDNF …
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