Il-17a damages the blood–retinal barrier through activating the janus kinase 1 pathway
Blood–retinal barrier (BRB) dysfunction underlies macular oedema in many sight-
threatening conditions, including diabetic macular oedema, neovascular age-related
macular degeneration and uveoretinitis. Inflammation plays an important role in BRB
dysfunction. This study aimed to understand the role of the inflammatory cytokine IL-17A in
BRB dysfunction and the mechanism involved. Human retinal pigment epithelial (RPE) cell
line ARPE19 and murine brain endothelial line bEnd. 3 were cultured on transwell …
threatening conditions, including diabetic macular oedema, neovascular age-related
macular degeneration and uveoretinitis. Inflammation plays an important role in BRB
dysfunction. This study aimed to understand the role of the inflammatory cytokine IL-17A in
BRB dysfunction and the mechanism involved. Human retinal pigment epithelial (RPE) cell
line ARPE19 and murine brain endothelial line bEnd. 3 were cultured on transwell …
[PDF][PDF] IL-17A Damages the Blood-Retinal Barrier through Activating the Janus Kinase 1 Pathway. Biomedicines. 2021; 9: 831
Blood–retinal barrier (BRB) dysfunction underlies macular oedema in many sightthreatening
conditions, including diabetic macular oedema, neovascular age-related macular
degeneration and uveoretinitis. Inflammation plays an important role in BRB dysfunction.
This study aimed to understand the role of the inflammatory cytokine IL-17A in BRB
dysfunction and the mechanism involved. Human retinal pigment epithelial (RPE) cell line
ARPE19 and murine brain endothelial line bEnd. 3 were cultured on transwell membranes …
conditions, including diabetic macular oedema, neovascular age-related macular
degeneration and uveoretinitis. Inflammation plays an important role in BRB dysfunction.
This study aimed to understand the role of the inflammatory cytokine IL-17A in BRB
dysfunction and the mechanism involved. Human retinal pigment epithelial (RPE) cell line
ARPE19 and murine brain endothelial line bEnd. 3 were cultured on transwell membranes …
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