Image classification of experimental yields for cardiomyocyte cells differentiated from human induced pluripotent stem cells

S Mohammadi, F Finklea, M Hashemi, E Lipke… - Computer aided …, 2022 - Elsevier
Cardiovascular diseases (CVDs) are the number one cause of death worldwide. Mass
production of engineered heart tissue using differentiation of human-induced pluripotent
stem cells (hiPSCs) can substitute a large number of the lost heart muscle cells in patients
with CVDs. However, the scale-up of the differentiation systems for heart tissue, ie,
cardiomyocyte (CM), production is challenging because many parameters affect the
process. Machine learning (ML) techniques can be employed to identify critical process …
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