… Results The major biologic effects of imiquimod are mediated through … , imiquimod induces
apoptosis of tumour cells at higher concentrations. The pro‐apoptotic activity of imiquimod …

… Imiquimod is an immune response modifier commercially available as a 3.75 and 5%
cream. Topical imiquimod … on the mechanism of action of topical imiquimod, its FDA ‐approved …

Imiquimod, the first of a new class of compounds called immune response modifiers, is a
non-nucleoside, low modular weight, heterocyclic amine (imidizoquinolone) with the chemical …

… Imiquimod is formulated as a 5% cream; each gram of cream con- tains 50 mg of imiquimod.This
review examines the role of imiquimod 5% cream in the treatment of external genital …

… A clinical response with imiquimod is accompanied by a decrease in the amount of HPV
DNA and of messenger RNA for HPV proteins L1 and E7 [12] ; hence it is postulated that …

… , lacked imiquimod-mediated gene activation. Patients responding to topical imiquimod
treatment … Hence, imiquimod modulates IFN signal transduction to enhance transcription of IFN-α …

… , imiquimod is unique in that it activates immune function. The exact mechanism of imiquimod’…
Although in vitro studies have shown that imiquimod has no direct antiviral effects, the drug …

A central development of the past decade has been in our understanding of the interactions
between, and interdependence of, the innate and adaptive immune responses. Innate …

… This review serves to present new developments and applications of imiquimod. … imiquimod
treatment of genital warts have higher constitutive pretreatment levels of STAT‐1. Imiquimod …

… of action of imiquimod, current FDA-approved and non-FDA-approved uses of imiquimod,
and key … Common skin conditions that may be eradicated with imiquimod are emphasized. …