Immune factors in narcolepsy

N Langdon, C Lock, K Lock, D Lock, R Lock, H Lock… - Sleep, 1986 - academic.oup.com
… sleep factor in the blood or in the cerebrospinal fluid of narcoleptic subjects, and no unequivocal
marker of cellular immunity … It is highly likely that the narcoleptic syndrome is an immune-…

Narcolepsy as an immune‐mediated disease

AK De la Herrán-Arita, F García-García - Sleep disorders, 2014 - Wiley Online Library
factors, contributed to the increased incidence of narcolepsy in HLA DQB1*06:02-positive
children. In most, if not all the models where molecular mimicry has been used to induce an …

The immune basis of narcolepsy: what is the evidence?

S Taheri - Sleep medicine clinics, 2017 - sleep.theclinics.com
… 1 narcolepsy is closely associated with HLA DQB1*0602. This suggests that an autoimmune
process is involved in type 1 narcolepsy. … hypothalamus in sleep and narcolepsy is now well …

Narcolepsy: immunological aspects

S Overeem, JL Black III, GJ Lammers - Sleep medicine reviews, 2008 - Elsevier
… knowledge on (possible) immune mechanisms in the pathophysiology of narcolepsy. …
There have been several case-reports of secondary narcolepsy in patients with auto-immune

Narcolepsy: a model interaction between immune system, nervous system, and sleep-wake regulation

D Latorre, F Sallusto, CLA Bassetti… - Seminars in …, 2022 - Springer
… recent data on the involvement of the immune system in narcolepsy [8, 9] opened research
for … The purpose of this review is to provide an update on the current knowledge of narcolepsy

[HTML][HTML] The autoimmune basis of narcolepsy

J Mahlios, AK De la Herrán-Arita, E Mignot - Current opinion in …, 2013 - Elsevier
… Genome-wide association studies have strengthened the association between narcolepsy
and immune system gene polymorphisms, including the identification of polymorphisms in the …

Cytokines in narcolepsy: A systematic review and meta-analysis

S Mohammadi, M Mayeli, A Saghazadeh, N Rezaei - Cytokine, 2020 - Elsevier
… There is a higher risk of narcolepsy among populations where HLA subtype DQB1*0602 is
present [3]. It could be explained by the immune-mediated destruction of hypocretin neurons …

Genetic association, seasonal infections and autoimmune basis of narcolepsy

AK Singh, J Mahlios, E Mignot - Journal of autoimmunity, 2013 - Elsevier
… , it will be important to understand how the immune targets neurons such as hypocretin …
immune system presents unique challenges in finding a mechanism for the cause of narcolepsy

The immune system, the brain and narcolepsy

E Mignot, A Aran - Future Neurology, 2009 - Taylor & Francis
… as a marker for narcolepsy across multiple ethnic groups (… Although rs1154155 only confers
a small risk for narcolepsy … with narcolepsy and age-matched controls for markers of immune

CSF immune variables in patients with narcolepsy

S Fredrikson, B Carlander, M Billiard… - Acta neurologica …, 1990 - Wiley Online Library
… of diseases in which immune mediated pathogenesis are … of an association between
narcolepsy and multiple sclerosis (… have immune mediated pathogenesis; 4) the onset of …