Immunogenicity of BA. 5 bivalent mRNA vaccine boosters

AY Collier, J Miller, NP Hachmann… - … England Journal of …, 2023 - Mass Medical Soc
… We evaluated immune responses in 15 participants who had received the original
monovalent mRNA boosters and in 18 participants who had received the bivalent mRNA …

[HTML][HTML] Immunogenicity of the BA. 5 Bivalent mRNA Vaccine Boosters

YC Ai-ris, J Miller, NP Hachmann, K McMahan, J Liu… - BioRxiv, 2022 - ncbi.nlm.nih.gov
… Our data demonstrate that both monovalent and bivalent mRNA boosters markedly … BA.5
NAb titers were comparable following monovalent and bivalent mRNA boosters, with a …

Safety and immunogenicity of Omicron BA. 4/BA. 5 bivalent vaccine against covid-19

S Chalkias, J Whatley, F Eder, B Essink, S Khetan… - medRxiv, 2022 - medrxiv.org
BA.5 and omicron XBB.1, a recombinant of BA.2.10.1 and BA.… mRNA-1273.222 interim
safety and immunogenicity results … bivalent booster vaccines, mRNA-1273.222 and mRNA-…

Bivalent SARS-CoV-2 mRNA vaccines increase breadth of neutralization and protect against the BA. 5 Omicron variant in mice

SM Scheaffer, D Lee, B Whitener, B Ying, K Wu… - Nature medicine, 2023 - nature.com
… In this study, we evaluated the immunogenicity and protective efficacy of two, … mRNA-1273.214
or mRNA-1273.222 boosters. Thus, bivalent mRNA vaccine boosters that include mRNAs

Safety of BA. 4-5 or BA. 1 bivalent mRNA booster vaccines: nationwide cohort study

NW Andersson, EM Thiesson, JV Hansen, A Hviid - bmj, 2023 - bmj.com
booster) to the general population aged ≥50 years. Regulatory safety evaluations of the
adapted bivalent mRNA booster vaccinesmRNA vaccines, and clinical data on immunogenicity

Comparative effectiveness of bivalent BA. 4-5 and BA. 1 mRNA booster vaccines among adults aged≥ 50 years in Nordic countries: nationwide cohort study

NW Andersson, EM Thiesson, U Baum, N Pihlström… - bmj, 2023 - bmj.com
… studies on immunogenicity have shown diverging results … dose vaccination with the bivalent
BA.4-5 and BA.1 boosters … fourth dose vaccination, age, sex, region of residence, vaccination

SARS-CoV-2 neutralising antibodies after a second BA. 5 bivalent booster

Q Wang, A Bowen, J Ho, RM Zhang, R Valdez… - The Lancet, 2023 - thelancet.com
… To enhance immunity to evolving SARS-CoV-2 variants, updated bivalent mRNA vaccines
targeting both the omicron BA.5 and ancestral D614G spike proteins were introduced in …

Relative effectiveness of monovalent and bivalent mRNA boosters in preventing severe COVID-19 due to omicron BA. 5 infection up to 4 months post-administration in …

A Mateo-Urdiales, C Sacco, EA Fotakis… - The Lancet Infectious …, 2023 - thelancet.com
… second booster with monovalent or bivalent mRNA vaccines … omicron BA.5, a second
booster dose of an mRNA vaccine … -19 compared with a first booster dose received at least 120 …

Original SARS-CoV-2 monovalent and Omicron BA. 4/BA. 5 bivalent COVID-19 mRNA vaccines: phase 2/3 trial interim results

S Chalkias, JL Whatley, F Eder, B Essink, S Khetan… - Nature Medicine, 2023 - nature.com
… Herein, we summarize the interim safety and immunogenicity results of the mRNA-1273.222 …
BA.5-containing bivalent booster mRNA-1273.222 was similar to that of prior doses of …

Bivalent COVID-19 mRNA booster vaccination (BA. 1 or BA. 4/BA. 5) increases neutralization of matched Omicron variants

DN Springer, M Bauer, I Medits, JV Camp, SW Aberle… - npj Vaccines, 2023 - nature.com
… by BA.5-bivalent booster vaccines 3,4 . Of note, our results showed only modestly increased
BA.5 … with previous studies 5,6,7,8,9,10,11 , whereas others suggested that the bivalent-…