Folate receptor α (FRα) has emerged as a potential cancer therapy target with several folate-
linked therapeutic agents currently undergoing clinical trials. In addition, FRα expression in
tumors may offer prognostic significance. Most studies on FRα expression used reverse
transcriptase polymerase chain reaction or cytofluorimetric assays. The applicability of such
methods to paraffin-embedded tissues is limited. The aims of this study were to assess the
feasibility of immunohistochemistry in detecting FRα expression and to assess the patterns …