Impact of polymorphism in sulfotransferase gene on the risk of lung cancer
Sulfotransferases (SULTs) are very important multifunctional enzymes that catalyze
sulfonate conjugation, which is an important pathway in the phase II metabolism of
numerous endogenous and exogenous compounds. Sulfotransferase 1A1 (SULT1A1) is
active toward a wide range of substrates, including environmental and tobacco carcinogens.
This case-control study involved collection of peripheral blood samples (2–5 mL) of 103 lung
cancer patients and 122 controls from North Indian subjects. The SULT1A1 polymorphism …
sulfonate conjugation, which is an important pathway in the phase II metabolism of
numerous endogenous and exogenous compounds. Sulfotransferase 1A1 (SULT1A1) is
active toward a wide range of substrates, including environmental and tobacco carcinogens.
This case-control study involved collection of peripheral blood samples (2–5 mL) of 103 lung
cancer patients and 122 controls from North Indian subjects. The SULT1A1 polymorphism …
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