Implanted neural progenitor cells regulate glial reaction to brain injury and establish gap junctions with host glial cells
Transplantation of neural stem/progenitor cells (NPCs) in the lesioned brain is able to
restore morphological and physiological alterations induced by different injuries. The local
microenvironment created at the site of grafting and the communication between grafted and
host cells are crucial in the beneficial effects attributed to the NPC implants. We have
previously described that NPC transplantation in an animal model of central axotomy
restores firing properties and synaptic coverage of lesioned neurons and modulates their …
restore morphological and physiological alterations induced by different injuries. The local
microenvironment created at the site of grafting and the communication between grafted and
host cells are crucial in the beneficial effects attributed to the NPC implants. We have
previously described that NPC transplantation in an animal model of central axotomy
restores firing properties and synaptic coverage of lesioned neurons and modulates their …
[引用][C] Implanted neural progenitor cells regulate glial reaction to brain injury and establish gap junctions with host glial cells
R Talaverón Aguilocho… - GLIA, 62 (4), 623 …, 2014 - Wiley-Blackwell
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