The objective of this paper is to investigate the in vivo anti-tumor effect by dual release of
cisplatin (CDDP) and adriamycin (ADM) from a biodegradable hydrogel. Hydrogels with
different water contents were prepared through the chemical crosslinking of gelatin by
various concentrations of glutaraldehyde. Aqueous solution of CDDP, ADM or their mixture
(CDDP+ ADM) was impregnated into the freeze-dried hydrogel, followed by air-drying to
obtain the dried hydrogel incorporating the corresponding drug. Irrespective of the hydrogel …

IN VIVO ANTI-TUMOR EFFECT OF DUAL RELEASE OF CISPLATIN AND ADRIAMYCIN FROM
BIODEGRADABLE GELATIN HYDROGEL | International Journal of Gynecologic Cancer …