Serious scientific Research in the field of cosmetics has speared headed the growth of cosmetic industry, which adds undeniable credibility to the products. Many a time, a clinically simple, non-invasive dermatological technique is required to study the effect of the products in real time. Raman spectroscopy can be employed in his regard as it is a versatile technique which can be employed to study the nature and effects of these cosmetic products. In this short communication, we are reporting the study on the effect of fairness creams available in the market for the general Indian populace using Raman spectroscopy.