Inflammation and neutrophil immunosenescence in health and disease: Targeted treatments to improve clinical outcomes in the elderly
… an abnormal and sustained inflammatory response, with neutrophils being key effector cells
in … alteration of neutrophil functions in a number of chronic inflammatory diseases and during …
in … alteration of neutrophil functions in a number of chronic inflammatory diseases and during …
Inflammation and aging: signaling pathways and intervention therapies
… Immunosenescence of neutrophils occurs in a low-grade inflammatory environment, with
specific abnormalities in their metabolism and function, including decreased phagocytic …
specific abnormalities in their metabolism and function, including decreased phagocytic …
Phosphoinositide 3-kinase inhibition restores neutrophil accuracy in the elderly: toward targeted treatments for immunosenescence
… a range of inflammatory stimuli in migrating neutrophils isolated from healthy older subjects.
Cross… “bystander” tissue damage and heighten inflammation as a result of excess proteinase …
Cross… “bystander” tissue damage and heighten inflammation as a result of excess proteinase …
Immunosenescence, inflammaging, and frailty: role of myeloid cells in age-related diseases
A Bleve, F Motta, B Durante, C Pandolfo… - Clinical reviews in …, 2022 - Springer
… neutrophils; this critically perpetuates the pro-inflammatory responses [64, 65]. Classically
activated macrophages are professional antigen-presenting cells (APCs) that can stimulate T-…
activated macrophages are professional antigen-presenting cells (APCs) that can stimulate T-…
Immunosenescence: molecular mechanisms and diseases
Z Liu, Q Liang, Y Ren, C Guo, X Ge, L Wang… - … and targeted therapy, 2023 - nature.com
… This chronic inflammation is a typical phenomenon linked to immunosenescence and it is
considered the major … Age-regulated tissue-specific macrophages and neutrophils may cause …
considered the major … Age-regulated tissue-specific macrophages and neutrophils may cause …
Immunosenescence and inflammaging in the aging process: age-related diseases or longevity?
… , immunosenescence has been considered detrimental because it may lead to a low-grade,
sterile chronic inflammation … The aged neutrophils (CD10 neg ) are accumulated in the skin …
sterile chronic inflammation … The aged neutrophils (CD10 neg ) are accumulated in the skin …
Accelerated immunosenescence, oxidation and inflammation lead to a higher biological age in COPD patients
… Thus, the purpose of the present work was to investigate several functions of circulating
neutrophils (adherence, chemotaxis, phagocytosis and superoxide anion stimulation capacity) …
neutrophils (adherence, chemotaxis, phagocytosis and superoxide anion stimulation capacity) …
[PDF][PDF] Inflammation and neutrophil immunosenescence in health and disease
W Drew, D Wilson, E Sapey - core.ac.uk
… an abnormal and sustained inflammatory response, with neutrophils being key effector cells
in … alteration of neutrophil functions in a number of chronic inflammatory diseases and during …
in … alteration of neutrophil functions in a number of chronic inflammatory diseases and during …
The role of immunosenescence in the development of age-related diseases
T Fülöp, G Dupuis, JM Witkowski… - Revista de investigacion …, 2016 - medigraphic.com
… Indeed, the number of neutrophils was reported to be relatively high in the elderly, …
inflammation related to immunosenescence contributes to the development of Alzheimer’s disease (…
inflammation related to immunosenescence contributes to the development of Alzheimer’s disease (…
Interconnections between inflammageing and immunosenescence during ageing
… to significant pro-inflammatory signalling and highlight the … immunosenescence, and
inflammation in driving poor health … and neutrophils, reduced levels of the most pro-inflammatory …
inflammation in driving poor health … and neutrophils, reduced levels of the most pro-inflammatory …