BCL-2 (-938C > A) polymorphism is associated with breast cancer susceptibility

N Zhang, X Li, K Tao, L Jiang, T Ma, S Yan, C Yuan… - BMC medical …, 2011 - Springer
… Furthermore, we also studied the effects of this SNP on Bcl-2 … the effect of this polymorphism
on Bcl-2 expression in vitro and found that allele A was associated with the lower level of Bcl-…

Role of Bcl-2-938 C> A polymorphism in susceptibility and prognosis of cancer: a meta-analysis

X Zhang, W Weng, W Xu, Y Wang, W Yu, X Tang… - Scientific Reports, 2014 - nature.com
… studies have reported that Bcl-2 -938C>A promoter … Bcl-2 -938C>A polymorphism can
influence the susceptibility of cancer and to evaluate the prognostic significance of Bcl-2 -938C

BCL-2 (-938C> A) single-nucleotide variant and susceptibility to diffuse large B cell lymphoma

ES Essa, FES Morsy, GAEF Tawfeek… - Menoufia Medical …, 2022 - menoufia-med-j.com
… the studied cases, we found that the Bcl2938C>A polymorphism could not influence
either DLBCL patients’ clinical outcome or survival rate. These results met the studies done by …

The-938A/A genotype of BCL2 gene is associated with esophageal cancer

Z Liu, R Sun, W Lü, C Dang, Y Song, C Wang… - Medical Oncology, 2012 - Springer
… There appeared to be an impact of BCL2 -938A/A genotype … and neoplastic events are
influenced by genetic background. … was associated with the Bcl-2 protein expression in …

The BCL-2 promoter (− 938C> A) polymorphism does not predict clinical outcome in chronic lymphocytic leukemia

MA Kaderi, M Norberg, F Murray, M Merup… - Leukemia, 2008 - nature.com
… In summary, the current study shows that the clinical impact of the BCL2 polymorphism in
CLL is limited, since the presence of the BCL-2 (−938C>A) polymorphism did not significantly …

CC genotype of anti-apoptotic gene BCL-2 (− 938 C/A) is an independent prognostic marker of unfavorable clinical outcome in patients with non-small-cell lung …

J Javid, R Mir, M Mirza, A Imtiyaz, Y Prasant… - Clinical and …, 2015 - Springer
… study was to analyze the possible influence of the (−938C… BCL-2938C/A genotype show
a close correlation with the previous Bcl-2 expression studies, where the frequency of the BCL-…

Role of polymorphisms in BCL-2 and BAX genes in modulating the risk of developing non-Hodgkin lymphoma

WL Wang, YP Tao, XL Han, X Li, YM Zi… - Leukemia & …, 2014 - Taylor & Francis
… in the BCL-2 gene promoter has an impact on BCL-2 mRNA … the tumor cells directly; this
effect may be mediated by other … Furthermore, we cannot rule out that the BCL-2938C/A …

Molecular Evaluation of the Impact of Polymorphic Variants in Apoptotic (Bcl-2/Bax) and Proinflammatory Cytokine (TNF-α/IL-8) Genes on the Susceptibility and …

MS Moawadh, R Mir, FJ Tayeb, O Asim… - Current Issues in …, 2023 - mdpi.com
… The data from the current study provide partial but important evidence that polymorphisms
in apoptotic genes Bcl-2-938C>A and Bax-248G>A and pro-inflammatory cytokines IL-8 …

Study of regulatory promoter polymorphism (-938 C> A) of bcl2 gene in patients with gastric cancer

SH Mirmajidi, A Barzegar… - Journal of Mazandaran …, 2016 - jmums.mazums.ac.ir
… polymorphism of bcl2 gene promoter has been demonstrated to influence gastric cancer
susceptibility. In this research we studied the effect of -938C>A genotype on gastric cancer. …

Polymorphism in apoptotic BAX (-248G>A) gene but not in anti-apoptotic BCL2 (-938C>A) gene and its protein and mRNA expression are associated with cervical …

ATG Fernandes, NP Rocha, E Vendrame… - Apoptosis, 2015 - Springer
BCL-2-938C>A polymorphism was observed among the groups. BCL2-938C/A and A/A
homozygotes carriers had higher distribution of BCL-… study, we assessed the effects of BAX-248G…