The main objective of the current study is to evaluate tomato pomace silage as a source of roughage feed for lactating animals. Twenty lactating Egyptian buffaloes at the second/third season of lactation were used in the present study. The animals were randomly divided to two groups (ten buffaloes in each) using the complete random design. The animals were introduced to treatments starting on 70 DIM and continued for six weeks. The treatments were, control ration (R1) and it received a Corn Silage (CS) based ration supplemented with Concentrate Fed Mixture (CFM), Clover (C) and Rice Straw (RS) without Tomato Pomace Silage (TPS). The second ration (R2) was similar to the ration in first group with replacing clover by tomato pomace silage. The digestibility coefficients of dry matter, neutral and acid detergent fiber and nutritive values were increased (p<0.05) significantly with tomato pomace silage feeding. The protein and cellulose digestibility coefficients was negatively influenced (p<0.05) by tomato pomace feeding. The feeding of tomato pomace did not alter actual milk yield but it increased (p<0.05) 7% fat-corrected milk yield and milk fat percentage. Other milk composition percentages were not significantly affected. Feeding tomato pomace increased (p<0.05) proportions of polyunsaturated fatty acids, however, milk protein amino acid fraction was negatively affected in most cases. Inclusion of tomato pomace silage in the ration of lactating buffaloes improved feed utilization and economic efficiency compared to control ration. It was concluded that the nutritional value, feed conversion and economic efficiency of rations contained tomato pomace silage improved when used at rate 25% of ration without any adverse effect on performance of lactating buffaloes.