The female reproductive system is very complex and co-ordinated system that works well in the presence of hormonal and other signaling factors. Female reproduction is necessary for growth and maintenance of population. There has been a gradual increase in production and consumption of pesticides in agriculture to meet the population rising demands. But unconsciously during the last few decades, the use of these toxic chemicals has surpassed the tolerance level, creating imbalance in the system. Besides impairing the structural and functional aspects of female reproduction, they are altering the molecular, endocrinological, cytological and biochemical aspects as well, causing ovarian cycle irregularity and infertility. Thus, with the increase in pesticides consumption, there comes a need to investigate the various parameters which got affected due to the increased intake of these toxicants, giving emphasize on a upcoming field of Reproductive Toxicology. The review includes the effect of various toxicants on female reproduction and its system.