Factors that control the onset of folliculogenesis are critical to female gamete production, but
poorly understood. The aim of the present study was to investigate the effects of FSH and
EGF on the activation and growth of goat primordial follicles in vitro. To this end, pieces of
goat ovarian cortex were cultured in vitro for 1, 3 or 5 days, at 39° C in an atmosphere
containing 5% CO2, in minimum essential medium supplemented with insulin, transferrin,
selenium, pyruvate, glutamine, hypoxanthine, BSA, penicillin, streptomycin and fungizone …