Cerenkov luminescence (CL) is blue glow light produced by charged subatomic particles
travelling faster than the phase velocity of light in a dielectric medium such as water or
tissue. CL was first discovered in 1934, but for biomedical research it was recognized only in
2009 after advances in optical camera sensors brought the required high sensitivity.
Recently, applications of CL from clinical radionuclides have been rapidly expanding to
include not only preclinical and clinical biomedical imaging but also an approach to therapy …