A field experiment was conducted at AICRP on Weed Management Farm, BACA, AAU, Anand Gujarat during two consecutive Rabi season of 2016–17 and 2017–18 on loamy sand soil to study the effect of integrated weed management in garlic with and without rice straw mulch. The experiment was laid out in Split Plot design (SPT) with three replications. Rice straw mulch 5.0 t/ha applied after planting in conjunction with either application of oxyfluorfen 240 g/ha PE fb HW at 60 DAP or tank mix application of pendimethalin 500 g/ha + oxyfluorfen 120 g/ha EPoE recorded significantly lower density and dry weight of weeds at harvest with higher weed control efficiency (91.9 and 85.9%, respectively), bulb weight (17.3 and 14.0 g/bulb, respectively), bulb yield of garlic (8.83 and 7.91 t/ha, respectively) along with the highest net return and B:C ratio.