Interactions between the hepatitis C virus nonstructural 2 protein and host adaptor proteins 1 and 4 orchestrate virus release

F Xiao, S Wang, R Barouch-Bentov, G Neveu, S Pu… - MBio, 2018 - Am Soc Microbiol
adaptor; AP-1A; and AP-1B in HCV infection. We screened for interactions between HCV
proteins and the μ subunits of AP-1A, AP-1B, and AP-4 by mammalian cell-based protein

Interaction between hepatitis C virus proteins and host cell factors

TL Tellinghuisen, CM Rice - Current opinion in microbiology, 2002 - Elsevier
… the remaining viral non-structural proteins, as well as host cell … of host cell interactions
described for hepatitis C virus proteins… on HCV–host-protein interactions has been descriptive and …

Hepatitis C virus proteins: from structure to function

D Moradpour, F Penin - Hepatitis C virus: from molecular virology to …, 2013 - Springer
… link between replication complexes and viral assembly sites on … and/or by engaging in
interactions with host factors involved in … NS4B interacts with other viral nonstructural proteins and …

NS5A, a nonstructural protein of hepatitis C virus, binds growth factor receptor-bound protein 2 adaptor protein in a Src homology 3 domain/ligand-dependent manner …

SL Tan, H Nakao, Y He, S Vijaysri… - Proceedings of the …, 1999 - National Acad Sciences
host and viral proteases, resulting in at least nine mature viral structural and nonstructural
proteins (… interaction with Grb2, an adaptor protein that consists of one SH2 domain flanked by …

The nonstructural NS5A protein of hepatitis C virus: an expanding, multifunctional role in enhancing hepatitis C virus pathogenesis

GR Reyes - Journal of biomedical science, 2002 - Springer
… The result of these biological interactions between virus and host is the establishment of
a … Expression of hepatitis C virus proteins interferes with the antiviral action of interferon …

Structural and functional studies of nonstructural protein 2 of the hepatitis C virus reveal its key role as organizer of virion assembly

V Jirasko, R Montserret, JY Lee, J Gouttenoire… - PLoS …, 2010 - journals.plos.org
… understanding of pathogens and how they interact with host organisms. … protein participates
in multiple interactions with E2, p7, NS3 and NS5A that appear to recruit the viral proteins to …

Hepatitis C virus infection protein network

…, M Vidal, P André, C Rabourdin‐Combe… - Molecular systems …, 2008 - embopress.org
… A proteome-wide mapping of interactions between hepatitis C virus (HCV) and human
proteins was … level by mapping the interactions of a large number of viral proteins with host

Unfolded protein response in hepatitis C virus infection

SW Chan - Frontiers in microbiology, 2014 - frontiersin.org
… Understanding how the virus interacts with the host is key to answer these questions. …
interacts with ATF6 to modulate UPR. The hepatitis C virus (HCV) non-structural (NS) 4B protein

HCV core protein and virus assembly: what we know without structures

K Gawlik, PA Gallay - Immunologic research, 2014 - Springer
Hepatitis C virus (HCV) is a blood-born, hepatotropic virus and a major cause of chronic …
the coordinated interactions between viral structural and nonstructural proteins and host factors […

Landscape of protein-protein interactions during hepatitis C virus assembly and release

A Matthaei, S Joecks, A Frauenstein… - Microbiology …, 2024 - Am Soc Microbiol
viral constructs with epitope-tagged envelope protein 2 (E2), protein (p) 7, or nonstructural
protein … provide a map of host proteins interacting with HCV assembly proteins, and they give …