Interactome analyses of Salmonella pathogenicity islands reveal SicA indispensable for virulence

C Lahiri, S Pawar, R Sabarinathan, MI Ashraf… - Journal of theoretical …, 2014 - Elsevier
Abstract Background Serovars of Salmonella enterica, namely Typhi and Typhimurium,
reportedly, are the bacterial pathogens causing systemic infections like gastroenteritis and
typhoid fever. To elucidate the role and importance in such infection, the proteins of the Type
III secretion system of Salmonella pathogenicity islands and two component signal
transduction systems, have been mainly focused. However, the most indispensable of these
virulent ones and their hierarchical role has not yet been studied extensively. Results We …
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