Interleukin‐4 single nucleotide polymorphisms in juvenile systemic lupus erythematosus
M Mahmoudi, F Tahghighi, V Ziaee… - International journal …, 2014 - Wiley Online Library
Juvenile systemic lupus erythematosus (JSLE) is a chronic, recurrent multisystem
inflammatory disease, caused by a combination of environmental events and genetic risk
factors. As cytokines, including interleukin‐4 (IL‐4), seem to have a role in the pathogenesis
of JSLE, the investigation was performed to evaluate the associations of specific single
nucleotide polymorphisms (SNP s) of IL‐4 and IL‐4RA genes in a case–control study. Fifty‐
nine patients with JSLE were recruited in this study as patients' group and compared with …
inflammatory disease, caused by a combination of environmental events and genetic risk
factors. As cytokines, including interleukin‐4 (IL‐4), seem to have a role in the pathogenesis
of JSLE, the investigation was performed to evaluate the associations of specific single
nucleotide polymorphisms (SNP s) of IL‐4 and IL‐4RA genes in a case–control study. Fifty‐
nine patients with JSLE were recruited in this study as patients' group and compared with …
INTERLEUKIN-4 SINGLE NUCLEOTIDE POLYMORPHISMS IN JUVENILE SYSTEMIC LUPUS ERYTHEMATOSUS
SF TAHGHIGHI, V ZIAEE, MM MORADINEJAD… - 2013 - sid.ir
Background: Juvenile systemic lupus erythematosus (JSLE) is a chronic, recurrent
multisystem inflammatory disease, caused by a combination of environmental events and
genetic risk factors. As cytokines, including interleukin-4 (IL-4), seem to have a role in the
pathogenesis of JSLE, this investigation was performed to evaluate the associations of
specific single-nucleotide polymorphisms (SNPs) of IL-4 gene in a case control association
study. Methods: Fifty nine patients with JSLE were recruited in this study as patients' group …
multisystem inflammatory disease, caused by a combination of environmental events and
genetic risk factors. As cytokines, including interleukin-4 (IL-4), seem to have a role in the
pathogenesis of JSLE, this investigation was performed to evaluate the associations of
specific single-nucleotide polymorphisms (SNPs) of IL-4 gene in a case control association
study. Methods: Fifty nine patients with JSLE were recruited in this study as patients' group …