Internal quality control and external quality assurance in testing for antiphospholipid antibodies: Part I—Anticardiolipin and anti-β2-glycoprotein I antibodies

EJ Favaloro, L Wheatland, S Jovanovich… - … in thrombosis and …, 2012 - thieme-connect.com
Over 30 years since it was first described as a discrete clinical entity, the antiphospholipid
antibody syndrome (APS) remains a challenge for both laboratory workers and clinicians in
a wide range of specialties. In addition to the presence of appropriate clinical features, the
diagnosis of APS also fundamentally requires the finding of positive antiphospholipid
antibody (aPL) test result (s), which comprise clot-based assays for the identification of lupus
anticoagulant (LA) and immunologic (“solid-phase”) assays such as anticardiolipin …

Internal quality control and external quality assurance in testing for antiphospholipid antibodies: part II—lupus anticoagulant

EJ Favaloro, R Bonar, K Marsden - Seminars in thrombosis and …, 2012 - thieme-connect.com
In addition to the presence of appropriate clinical features, the diagnosis of the
antiphospholipid antibody syndrome (APS) fundamentally requires the finding of positive
antiphospholipid antibody (aPL) test result (s), with these comprising clot-based assays for
the identification of lupus anticoagulant (LA) and immunologic (“solid-phase”) assays such
as anticardiolipin antibodies (aCL) and anti-β 2-glycoprotein I antibodies (aβ 2 GPI). This
article is the second of two that review the process for, and provide recommendations to …
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