Intraoperative laser speckle contrast imaging to assess vessel flow in neurosurgery: a pilot study
METHODS: This is a single-center prospective observational study enrolling adult patients
requiring microsurgical treatment for brain vascular pathologies or brain tumors. Three
independent raters, blinded toward findings of FA, reviewed regions of interest (ROIs)
placed in exposed vessels and target structures. The primary end point was the validity of
LSCI for assessment of vessel flow as measured by the agreement with FA. The secondary
end point was objectivity, measured as the inter-rater agreement of LSCI findings …
requiring microsurgical treatment for brain vascular pathologies or brain tumors. Three
independent raters, blinded toward findings of FA, reviewed regions of interest (ROIs)
placed in exposed vessels and target structures. The primary end point was the validity of
LSCI for assessment of vessel flow as measured by the agreement with FA. The secondary
end point was objectivity, measured as the inter-rater agreement of LSCI findings …
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