Involvement of TLR2 and TLR4 and Th1/Th2 shift in inflammatory responses induced by fine ambient particulate matter in mice

C Zhao, J Liao, W Chu, S Wang, T Yang, Y Tao… - Inhalation …, 2012 - Taylor & Francis
… PM2.5 in mice can lead to acute inflammatory response locally and systemically. TLR2 and
TLR4 are involved in the process of inflammation, and they induce different effects in different …

Ambient fine particulate matter induces inflammatory responses of vascular endothelial cells through activating TLR-mediated pathway

Y Le, X Hu, J Zhu, C Wang… - … and Industrial Health, 2019 - journals.sagepub.com
role of Toll-like receptors (TLRs) on fine particulate matter (PM 2.5 )-induced inflammatory
responses … We found that the mRNA levels of TLR2, TLR4, and MyD88 in the mouse aortas of …

The innate and adaptive immune response induced by alveolar macrophages exposed to ambient particulate matter

R Miyata, SF van Eeden - Toxicology and applied pharmacology, 2011 - Elsevier
… -induced TLR4-mediated inflammatory response (TNF-α and IL-6 levels) and NF-κB activation
as elicited by comparison with SR-A−/− miceTh1/Th2 responses induced by macrophages …

Lipopolysaccharide attached to urban particulate matter 10 suppresses immune responses in splenocytes while particulate matter itself activates NF-κB

Y Song, T Ichinose, M He, C He, K Morita… - Toxicology …, 2016 - academic.oup.com
… bacteria can bind to TLR4 and activate the transcription factor … The mice were acclimated
for 1 week, and healthy mice were … However, chronic pollution-induced inflammation reactions

[HTML][HTML] … particulate matter induces airway inflammation by disturbing the balance between Th1/Th2 and regulation of GATA3 and Runx3 expression in BALB/c mice

L Pang, P Yu, X Liu, Y Fan… - Molecular medicine …, 2021 - spandidos-publications.com
inflammation response, especially in the asthmatic mouse … imbalance in Th1/Th2, has been
reported to be involved in … )2/TLR4/myeloid differentiation primary response protein M2yD88 …

Health effects of ambient particulate matter—biological mechanisms and inflammatory responses to in vitro and in vivo particle exposures

KL Maier, F Alessandrini, I Beck-Speier… - Inhalation …, 2008 - Taylor & Francis
… 24 h in nonsensitized mice induced no significant alterations in … differential expression of
Th1/Th2 associated chemoattractants … with LPS-induced TLR2-and TLR4 responses amplify the …

T-helper type 1-T-helper type 2 shift and nasal remodeling after fine particulate matter exposure in a rat model of allergic rhinitis

ZQ Guo, WY Dong, J Xu, ZC Hong… - American Journal of …, 2017 - journals.sagepub.com
… Remodeling occurs in all inflammatory responses, and the … The aim of the study was to
explore the expression of Th1Th2… assess nasal remodeling changes in rats with AR exposed to …

Elevated expression of miR-146, miR-139 and miR-340 involved in regulating Th1/Th2 balance with acute exposure of fine particulate matter in mice

T Hou, J Liao, C Zhang, C Sun, X Li, G Wang - International …, 2018 - Elsevier
particulate matter manifest not only inflammatory cell infiltration, but also accompanying change
… that exposure to ambient particulate matter can induce pro-inflammation release and Th1…

A traditional herbal formula, Deng-Shi-Qing-Mai-Tang, regulates TLR4/NF-κB signaling pathway to reduce inflammatory response in PM2. 5-induced lung injury

Y Zhou, J Liu, C Jiang, J Chen, X Feng, W Chen… - Phytomedicine, 2021 - Elsevier
… Studies revealed that particulate matter 2.5 (PM2.5) enters … , TLR4/NF-κB signaling pathways
are reported to play a role … in rats with PM2.5-induced lung injury and inflammation to test …

Biological effects of airborne fine particulate matter (PM2. 5) exposure on pulmonary immune system

T Wei, M Tang - Environmental toxicology and pharmacology, 2018 - Elsevier
… PM 2.5 can induce local or systematic inflammatory responses. This … of rats. The variation of
cytokines illustrated that the balance of … on the shift of Th1/Th2 mediated responses are both …