Involvement of serotonergic system in the antidepressant-like effect of piperine

QQ Mao, YF Xian, SP Ip, CT Che - Progress in Neuro …, 2011 - Elsevier
Piperine is a major alkaloid of black pepper (Piper nigrum Linn.) and long pepper (P.
longum Linn.), and its antidepressant-like effect has been previously demonstrated. The
purpose of this study was to explore the possible contribution of the serotonergic system in
the antidepressant-like effect of piperine in mice. The results showed that piperine
significantly reduced the immobility time in the forced swim test and tail suspension test in
mice. The anti-immobility effect of piperine in the forced swim test and tail suspension test …

Involvement of serotonergic system in the antidepressant-like effect of piperine.

MQQ Mao QingQiu, XYF Xian YanFang, ISP Ip SiuPo… - 2011 - cabidigitallibrary.org
Piperine is a major alkaloid of black pepper (Piper nigrum Linn.) and long pepper (P.
longum Linn.), and its antidepressant-like effect has been previously demonstrated. The
purpose of this study was to explore the possible contribution of the serotonergic system in
the antidepressant-like effect of piperine in mice. The results showed that piperine
significantly reduced the immobility time in the forced swim test and tail suspension test in
mice. The anti-immobility effect of piperine in the forced swim test and tail suspension test …
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