Isolation, Characterization and Anticancer Potential of Cytotoxic Triterpenes from Betula utilis Bark

T Mishra, RK Arya, S Meena, P Joshi, M Pal, B Meena… - PloS one, 2016 - journals.plos.org
Betula utilis, also known as Himalayan silver birch has been used as a traditional medicine
for many health ailments like inflammatation, HIV, renal and bladder disorders as well as
many cancers from ages. Here, we performed bio-guided fractionation of Betula utilis Bark
(BUB), in which it was extracted in methanol and fractionated with hexane, ethyl acetate,
chloroform, n-butanol and water. All six fractions were evaluated for their in-vitro anticancer
activity in nine different cancer cell lines and ethyl acetate fraction was found to be one of the …

Isolation, characterization and anticancer potential of cytotoxic triterpenes from Betula utilis Bark.

TM Tripti Mishra, RK Arya, SM Sanjeev Meena… - 2016 - cabidigitallibrary.org
Betula utilis, also known as Himalayan silver birch has been used as a traditional medicine
for many health ailments like inflammation, HIV, renal and bladder disorders as well as
many cancers from ages. Here, we performed bio-guided fractionation of Betula utilis Bark
(BUB), in which it was extracted in methanol and fractionated with hexane, ethyl acetate,
chloroform, n-butanol and water. All six fractions were evaluated for their in-vitro anticancer
activity in nine different cancer cell lines and ethyl acetate fraction was found to be one of the …
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