Background: This study was the first national survey ever conducted in Greece aiming to monitor the level of stigma Greeks hold against people with schizophrenia (PWS).

Aim: To investigate sources, degree of knowledge and attitudes towards PWS in Greece.

Method: A cross-sectional nationwide survey was conducted by face-to-face household interviews ( n = 1,199, aged 15 years and over).

Results: Television was the main source of information (65.9%). Negative portrayals of PWS were recalled by 60.5%. Only 27.7% attributed schizophrenia to a combination of psychosocial, genetic and environmental factors. Respondents believed that PWS are dangerous (74.6%), have split personalities (81.3%) and cannot work (83.2%). Regarding attitudes, a negative relationship between closeness and social distance was observed. Most respondents (92.1%) would not marry someone with schizophrenia, half (50.5%) would be disturbed by working with PWS and one third (32.9%) would feel afraid to start a conversation. Urban residence and higher education were generally associated with better knowledge and more positive attitudes towards PWS.

Conclusions: Knowledge about schizophrenia in Greece is poor. The Greek public has stigmatizing attitudes towards PWS. Educational interventions should especially target rural and semi-urban residents of a lower educational level. The role of television can be crucial.