Aim: To determine the knowledge of childhood blindness among mothers visiting a children’s hospital in the Kumasi metropolis, Ghana.

Methods: This hospital-based cross-sectional study was conducted from January to March, 2017. One hundred (100) mothers who visited the Asokwa Children’s hospital were conveniently sampled for this study. A structured questionnaire was used to collect data on demographics, knowledge on childhood blindness and their causes, childhood blindness prevention and treatment and sources of knowledge. Data were entered and analyzed by IBM SPSS Statistics (version 23). Binary logistic regression models were used to identify associated factors. Odds ratios with 95% Confidence interval were computed to assess the strength and significant level of associations.

Results: The mean age (±SD) of the sampled mothers was 32.31 (±5.56) years. The study showed that 76 (76%) mothers had good knowledge about childhood blindness.‘Ocular injuries’ was the most identified disease that could cause childhood blindness, with ‘hereditary retinal dystrophies’ being the least. The main source of maternal knowledge on childhood blindness was during pregnancy care (55%: antenatal and postnatal care). Mothers’ educational level was the only factor that significantly influenced maternal knowledge of childhood blindness (p< 0.001).

Conclusion: Maternal knowledge about childhood blindness was high. However, intervention modalities that focus on increasing level of parental education, access to antenatal and postnatal care services, and promoting girl-child education should be promoted to help continually raise awareness and knowledge of childhood blindness.