[HTML][HTML] LHRH-conjugated drugs as targeted therapeutic agents for the specific targeting and localized treatment of triple negative breast cancer
… drug specificity in the targeting of TNBC. In this paper, LHRH-conjugated prodigiosin and
LHRH-conjugated paclitaxel were studied as model cancer drugs. These were synthesized by …
LHRH-conjugated paclitaxel were studied as model cancer drugs. These were synthesized by …
LHRH-targeted drug delivery systems for cancer therapy
… local concentrations of the targeting moiety and the drug, … discussed studies, LHRH-conjugated
dextran nanoparticles … be utilized as self-therapeutic agents as well as nanocarriers…
dextran nanoparticles … be utilized as self-therapeutic agents as well as nanocarriers…
Targeting luteinizing hormone-releasing hormone: a potential therapeutics to treat gynecological and other cancers
R Ghanghoria, P Kesharwani, RK Tekade… - Journal of Controlled …, 2018 - Elsevier
… and clinical impingement of the peptide is at both the diagnostic as well as therapeutic levels
[50]. Receptor mediated in vivo scintigraphy employs localization of radioactive molecule …
[50]. Receptor mediated in vivo scintigraphy employs localization of radioactive molecule …
LHRH-conjugated, PEGylated, poly-lactide-co-glycolide nanocapsules for targeted delivery of combinational chemotherapeutic drugs Docetaxel and Quercetin for …
… localization studies, which highlighted the higher tumor accumulation ability of the LHRH-conjugated …
out that the use of a combination of drugs DTX and QU gives enhanced anticancer …
out that the use of a combination of drugs DTX and QU gives enhanced anticancer …
Lipid-Based Nanocarrier by Targeting with LHRH Peptide: A Promising Approach for Prostate Cancer Radio-Imaging and Therapy
K De, SKE Tanbir, S Sinha… - Molecular …, 2024 - ACS Publications
… targeted administration of anticancer drugs, thus opening up the possibility of a drug delivery
system with precise control and targeting … improved efficacy for prostate cancer therapy. …
system with precise control and targeting … improved efficacy for prostate cancer therapy. …
LHRH-peptide conjugated dextran nanoparticles for targeted delivery of cisplatin to breast cancer
… of CDDP-loaded LHRH-conjugated targeted and non-targeted … drug release behavior,
prolonged blood circulation and enhanced tumor localization, the CDDP-loaded LHRH-targeted …
prolonged blood circulation and enhanced tumor localization, the CDDP-loaded LHRH-targeted …
[HTML][HTML] New drug delivery strategies targeting the GnRH receptor in breast and other cancers
HSA Ghaly, P Varamini - Endocrine-Related Cancer, 2021 - erc.bioscientifica.com
… is the poor accessibility of therapeutic agents, especially chemotherapeutic agents, to cancer
… addressed by targeting therapeutic agents exclusively to cancer cells via agents designed …
… addressed by targeting therapeutic agents exclusively to cancer cells via agents designed …
[HTML][HTML] A conjugate of methotrexate and an analog of luteinizing hormone releasing hormone shows increased efficacy against prostate cancer
S Zhu, Q Wang, J Jiang, Y Luo, Z Sun - Scientific reports, 2016 - nature.com
… The in vivo anti-tumor activity of the therapeutic agents were assessed on mice bearing PC-…
to the targeting features of [DLys 6 ]-LHRH-MTX that allow for better localization of treatment …
to the targeting features of [DLys 6 ]-LHRH-MTX that allow for better localization of treatment …
Targeted delivery of cisplatin by LHRH-peptide conjugated dextran nanoparticles suppresses breast cancer growth and metastasis
… cells, ∗∗ p < 0.01), demonstrating that the LHRH conjugated nanoparticles were
recognized by LHRH receptors on the surface of 4T1 cells and internalized through receptor-mediated …
recognized by LHRH receptors on the surface of 4T1 cells and internalized through receptor-mediated …
LHRH‐targeted redox‐responsive crosslinked micelles impart selective drug delivery and effective chemotherapy in triple‐negative breast cancer
K Xiao, Q Liu, N Suby, W Xiao… - Advanced …, 2021 - Wiley Online Library
… -LHRH conjugated PEG 5k -Cys 4 -L 8 -CA 8 telodendrimer, which will facilitate the precise
delivery of therapeutic drugs into breast cancer cells through specific … co-localization method. …
delivery of therapeutic drugs into breast cancer cells through specific … co-localization method. …